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Glycolysis
EC 2.7.1

Summary Of: Hexokinase

by duplication and fusion of a 50kD ancestral hexokinase similar to those of bacteria... but only in hexokinase II do both halves have functional active sites... of glucose by hexokinase to prepare it for later breakdown in order to provide energy... for the immediate phosphorylation of glucose by a hexokinase is to prevent diffusion out of the cell... This association confers hexokinase direct access to mitochondrially... Mitochondrial hexokinase is highly elevated in rapidly... bound hexokinase has been demonstrated to be the driving force...

Encyclodia Page On: Hexokinase

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Symbol(s) | Genetic data | Locus | Chr. 10 | isoforms | Taxa expressing | H. sapiens | homologs | domains | Cytoplasm | Mitochondrion | Plasma membrane | Catalytic activity | ATP | hexose | ADP | hexose | phosphate | Enzyme Regulation | Glc-6-P | Diseases | Hexokinase deficiency | Online 'Mendelian Inheritance in Man' | EC number | Entrez | OMIM | RefSeq | UniProt | Symbol(s) | Genetic data | Locus | Chr. 2 | EC number | Entrez | OMIM | RefSeq | UniProt | Symbol(s) | Genetic data | Locus | Chr. 5 | EC number | Entrez | OMIM | RefSeq | UniProt | Hexokinase: 1st glycolysis enzyme. Left: without glucose (shown the Glc binding pocket) (PDB code=1hkg). Right: with glucose (PDB code=2yhx) | | enzyme | phosphorylates | sugar | hexose | glucose | substrate | glucose-6-phosphate | bacteria | yeast | plants | vertebrates | ATP | isozymes | species | glycolysis | glycogen | mammalian | EC | Michaelis-Menten kinetics | inhibited | glucose-6-phosphate | Molecular weights | glucokinase | phosphorylation | glucokinase | cytoplasm | nucleus | liver | allosterically | liver | pancreas | hypothalamus | small intestine | neuroendocrine | carbohydrate metabolism | beta cells | islets | insulin | glucagon | alpha cells | hepatocytes | metabolic pathway | glycolysis | phosphorylation | Glucose | Glucose-6-phosphate | image:Glucose_wpmp.png | image:Glucose-6-phosphate_wpmp.png | ATP | ADP | | KEGG | KEGG | KEGG | KEGG | phosphate | glucose 6-phosphate | mitochondria | Otto Warburg | glucokinase | glycolysis | glycogen | insulin | Glucose 6-phosphatase | doi | v | d | Glycolysis | Metabolic Pathway | Glucose | Glucose-6-phosphate | Glucose-6-phosphate isomerase | Fructose 6-phosphate | 6-phosphofructokinase | Fructose 1,6-bisphosphate | Fructose bisphosphate aldolase | Dihydroxyacetone phosphate | Glyceraldehyde 3-phosphate | Triosephosphate isomerase | Glyceraldehyde 3-phosphate | Glyceraldehyde-3-phosphate dehydrogenase | | | | | | | | | | | | | | 1,3-Bisphosphoglycerate | Phosphoglycerate kinase | 3-Phosphoglycerate | Phosphoglycerate mutase | 2-Phosphoglycerate | Phosphopyruvate hydratase | Enolase | Phosphoenolpyruvate | Pyruvate kinase | Pyruvate | Pyruvate dehydrogenase | Acetyl-CoA | | | | | | CoA | | | | | | | v | d | Transferases | Phosphotransferases | kinases | EC | OH | Gluco- | Fructo- | Hepatic fructo- | Galacto- | Phosphofructo- | 1 | 2 | Riboflavin | Shikimate | Thymidine | NAD+ | Glycerol | Pantothenate | Mevalonate | Pyruvate | Deoxycytidine | PFP | Diacylglycerol | Bruton's tyrosine | Phosphoinositide 3 | Class I PI 3 | Class II PI 3 | Sphingosine | COOH | Phosphoglycerate | Aspartate | N | Creatine | PO4 | Phosphomevalonate | Adenylate | Nucleoside-diphosphate | P2O7 | Ribose-phosphate diphosphokinase | Thiamine pyrophosphokinase | nucleotidyl- | Integrase | PNPase | Polymerase | RNase PH | UDP-glucose pyrophosphorylase | Galactose-1-phosphate uridylyltransferase | Terminal deoxynucleotidyl transferase | RNA replicase | Reverse transcriptase | Telomerase | Transposase | N-acetylglucosamine-1-phosphate transferase | protein | Tyrosine | Serine/threonine-specific | v | Metabolism | carbohydrate metabolism | glycolysis | gluconeogenesis | enzymes | Glucokinase | Glucose 6-phosphatase | Glucose isomerase | Phosphofructokinase 1 | Fructose 1,6-bisphosphatase | Aldolase | Triosephosphate isomerase | Glyceraldehyde 3-phosphate dehydrogenase | Phosphoglycerate kinase | Phosphoglycerate mutase | Enolase | Pyruvate kinase | oxaloacetate | Pyruvate carboxylase | Phosphoenolpyruvate carboxykinase | lactate | Cori cycle | Lactate dehydrogenase | alanine | Alanine cycle | Alanine transaminase | glycerol | Glycerol kinase | Glycerol dehydrogenase | Phosphofructokinase 2 | Fructose 2,6-bisphosphatase | Bisphosphoglycerate mutase | disorders | Categories | Glycolysis | EC 2.7.1 |
This article is licensed under the GNU Free Documentation License. It uses material from the Wikipedia article "Hexokinase".